CANINE PARVOVIRUS
Parvovirus is a HIGHLY CONTAGIOUS virus that attacks
the intestines and causes sloughing of the inner layers of the intestine. The
most common symptoms of this disease (the "intestinal form") are vomiting and diarrhoea. Another less common form,
the "cardiac form", occurs in very young pups (less than 8 weeks of
age) and attacks the heart muscle, often resulting in sudden death.
Parvovirus is contagious
to dogs only - not to cats or people. Any age, breed, or sex of dog could be
affected by parvovirus. However, infection with parvovirus does not
automatically mean illness. Several factors such as age, environment, stress,
parasites, and general health status of each individual dog infected could
affect the severity of the disease. The degree of illness could range from very
mild to unapparent to very severe, often resulting in death. The disease is
usually more severe in young dogs (less than 6 months of age), old dogs, Rottweilers and Dobermans. The younger
and smaller the dog the greater the chance that it will not recover.
Parvovirus is resistant
to extremes of temperature (i.e. it survives freezing and extreme heat) and is
unharmed by detergents, alcohol and common disinfectants. Direct transmission occurs when an
infected dog comes in contact with a healthy dog. The virus is found in heavy
concentration in the infected dog’s stool. Because dogs will usually sniff
where another dog has eliminated, this faecal-oral
transmission is the most common method of transmission. The
virus particles can be easily spread by hands, shoes, clothing, or other
inanimate objects (fomites)
this is an indirect
source of transmission.
As many as 30 billion
parvovirus particles can be shed from the intestines of an infected dog in
every ounce of stool. The highest concentration of virus in the stool is seen
when the infected dog is showing signs of illness. A dog can however be a
source of infection to other dogs without it having observable signs of illness
(the disease may be incubating). Transmission can occur for at least 3 weeks after a dog become infected
with the virus. Chronic "carriers" are not known to exist as in other
viral diseases. Parvovirus in the environment can infect susceptible dogs for as long as 6 months once shed in the
stool.
Clinical signs include vomiting, fever,
loss of appetite, depression and bloody diarrhoea with
a very foul odour. Infected animals rapidly dehydrate and severe cases progress
to shock and death. Early, vigorous treatment of illness caused by canine
parvovirus infection can save lives.
Cardiac form (less than 8
weeks of age):
- Sudden death
- Crying, difficulty breathing, gasping for breath
- Extreme depression
- Weakness
- Unwillingness to nurse
- Irregular heartbeat
Intestinal form (any age
dog affected, but more severe in puppies):
- Depression
- Loss of appetite
- Fever (usually above 103F)
- Vomiting with or without blood
- Diarrhoea with or without blood (more serious if blood
present)
- Low white blood cell count(due to immunosuppression)
Treatment is aimed at maintaining
the normal body composition and preventing secondary bacterial infection.
Because this is a virus, there is NO
CURE. Death from parvovirus results from dehydration,
overwhelming secondary bacterial infection, blood loss from intestinal
haemorrhage, or heart attack from invasion of the heart muscle by the virus.
Early FLUID THERAPY is
the most important factor in treating dogs with parvovirus infection. The body
is normally about 80% water. Life is NOT possible when 12-15% of the normal
body fluids are lost. Intravenous fluids both re-hydrate the body and nourish
the sick dog.
Additional treatment
includes prevention of secondary bacterial infection and drugs to control
vomiting and diarrhoea. No food or water is given while the dog is vomiting.
Repeated laboratory tests are often necessary to monitor your pet’s while blood cell count and state of hydration.
HOSPITALIZATION enable vets to proved the
best medicine and is the best way to achieve success. There is NO GUARANTEE,
even with hospitalization, that your pet will survive.
With most dogs, there is at least a 70% survival rate. Very small (young)
puppies, Rottweilers and Dobermans usually only have
a 30-50% chance of survival. Length of treatment depends on the severity of
disease. Most dogs have to stay hospitalized for at least 2-4 days, but may
require treatment for as long as a week. Dogs that recover from parvo are often weak, making them even more susceptible to
other diseases, such as distemper. Dogs that recover from parvo
continue to spread the virus in the faeces for a month or longer.
Prevention\Control of parvovirus by
sanitation measures alone is extremely difficult because the virus is such a
resistant, hardy organism and because it is so easily spread. Contact with
other dogs, and especially their stool, should be minimized. Clorox diluted one
part to 30 parts water (4 oz Clorox in 1 gallon of water) has been effective in
disinfecting inanimate objects such as clothing, floors, kennels, etc. However,
it is impractical, if not impossible, to disinfect public streets, parks, etc.
Isolation of infected dogs is another method of control, moderately effective. both of these measures will help reduce the amount of
contagious virus in the environment, but only a full series of vaccinations,
with appropriate booster intervals, will help to control the source of
infection, the contagious shedding dog.
Guideline for young
puppies
1. Do
not take the puppy to the front yard, park, for a walk around the block, or to
pet stores. These are all places where infected dogs have been or presently
are.
2. Only
have the puppy around adult dogs that YOU KNOW are current on vaccinations.
There should be no contact with stray dogs or dogs that you are not sure of.
3. Do
not let the puppy be exposed to any other puppies. These pups could be
incubating the disease (and therefore be contagious) without showing signs of
illness.
4.
Always wash your hands after handling any dog.
Vaccination is the most effective
preventive measure for canine parvovirus disease. A properly immunized dog will
have circulating antibodies in the blood that will destroy parvovirus following
exposure. Dogs remain HIGHLY SUSCEPTIBLE to parvo
until 2-4 weeks after
the last injection of the immunization series.
The Role of Maternal
Antibody in Puppy Immunization
Maternal antibodies are
antibodies against viruses which are passed from the mother to the puppies
through the "first milk" or colostrum. They
provide the puppy with an immediate temporary or "passive" immunity.
The mother obtains these antibodies from prior vaccination or by natural
exposure to parvovirus. However, maternal antibody is a two-edged sword; it
protects the puppy against disease early in life, but it also blocks active
immunization (the puppies immune response to
vaccinations). In the case of parvovirus, maternal antibody can interfere with
vaccination for as long as 14 to 16
weeks of age in some pups. A refractory period can exist in
some pups where very low, almost undetectable levels of maternal antibody will
inhibit the vaccination process but will NOT PREVENT parvovirus infection.
Since the level of maternal antibody varies from puppy to puppy, IT IS
IMPORTANT TO BEGIN VACCINATION AT AN EARLY AGE AND REPEAT EVERY 3-4 WEEKS UNTIL
THE PUPPY IS AT LEAST 16-18 WEEKS OLD.
Notify the Vet if the
Following Occur
- YOUR DOG`S STOOL CONTAINS BLOOD, OR THE DIARRHEA RETURNS
- YOU CANNOT MEDICATE YOUR DOG AS INSTRUCTED
- YOUR DOG VOMITS OR IS RELUCTANT TO EAT
- THERE IS A CHANGE IN YOUR DOG`S GENERAL HEALTH
- YOUR DOG DOES NOT DRINK WATER